The Crucifer of Blood is a 1991 Anglo-US crime drama mystery film. It features Charlton Heston, Richard Johnson, Susannah Harker, Edward Fox, John Castle, and Simon Callow. A film adaptation of Sir Arthur Conan Doyle's classic Sherlock Holmes tale, The Sign of the Four. A beautiful young woman asks Holmes to help her father, a former army captain and hopeless opium addict break free of the curse surrounding a stolen treasure.