When the existence of a strain of plague (vaguely identified as pneumonic) is revealed at the US mission at the International Health Organization, three terrorists seek to blow up the US mission. Two of them are shot, one mortally, by security personnel but one escapes. The surviving terrorist is hospitalised and quarantined and identified as Swedish. Elena Stradner and US military intelligence Colonel Stephen Mackenzie argue over the nature of the strain, which Stradner suspects is a biological weapon but which Colonel Mackenzie claims was in the process of being destroyed.
The third terrorist, Eklund, escapes and stows away on a train bound from Geneva to Stockholm. Stradner believes that the train should be stopped so that the terrorist can be removed and quarantined, but Col. Mackenzie is concerned that all of the passengers on the train might be infected. Mackenzie insists on rerouting the train to a disused railway line which goes to a former Nazi concentration camp in Janov, Poland where the passengers will be quarantined. However, the line crosses a dangerously unsound steel arch bridge known as the Kasundruv Bridge or the "Cassandra Crossing", out of use since 1948 (former railway Zagorz-Solina-Turka-Lviv between Poland and Ukraine).....
Directed by George Pan Cosmatos
Produced by Carlo Ponti
Lew Grade
Screenplay by Tom Mankiewicz
Robert Katz
George Pan Cosmatos
Story by Robert Katz
George Pan Cosmatos
Starring Sophia Loren
Richard Harris
Burt Lancaster
Ava Gardner
Martin Sheen
O. J. Simpson
Lee Strasberg
Music by Jerry Goldsmith
Cinematography Ennio Guarnieri
Edited by Roberto Silvi
Françoise Bonnot